PW02-035 - A role for thermo-TRP channels in innate immunity?

نویسندگان

  • M Stoffels
  • T Remijn
  • LM Elders
  • HD de Koning
  • JW van der Meer
  • A Simon
چکیده

Introduction Exposure to cold can induce an exaggerated (local and systemic) inflammatory response in a number of rare disorders, including cryopyrin-associated periodic syndrome (CAPS), and idiopathic cold urticaria (CU). Although it is widely recognized that temperature sensing in neurons is mediated by several transient receptor potential (TRP) channels, it is not known how immune cells sense cold temperatures.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2013